Ag Biologicals PlatformPLANT TRAITS PLATFORMPilot Plant ServicesHow We Collaborate

Process Development & Pilot Plant Services

Commercialize your product with confidence. Go from lab scale to 3,000L at our pilot plant facility.

Who we serve

Our 1200 square meter facility supports a variety of biological production use cases that do not require food-grade or GMP certification. These include whole microbial ag biologicals, protein-based biologicals and small molecules used in nutraceuticals and fragrances. Our team and facility has experience scaling processes across a range of host organisms, including bacteria, yeast, and plant cell cultures.

Commercial terms

Any strains or processes that you transfer to us fully belong to you – your assets and data remain yours after we collaborate.

Three ways to work with us

01

Validate your process at scale

We welcome teams who have optimized their fermentation and downstream process at smaller scales and want to test it at up to 3,000L. Work with us onsite at West Sacramento!

02

Iterate on your process

Our facility and equipment is available to teams who want to iron out their fermentation and downstream process at various scales ranging from 15-3,000L. Work with us onsite at West Sacramento!

03

Outsource commercial process development

Starting from lab-scale media screening and fermentation process DoE, our experts use high throughput approaches to develop commercial-ready media and processes for your product.

End-to-end services. Choose your starting point.

START SMALL
Validate your process at scale

We welcome teams who have optimized their fermentation and downstream process at smaller scales and want to test it at up to 3,000L. Work with us onsite at West Sacramento!

VALIDATE & ITERATE
Pilot-scale media and process optimization

We confirm that your media and process parameters deliver the results you need at volumes ranging from 15-3,000L. We begin testing downstream process compatibility at 300L scale.

STABILIZE & CONCENTRATE
Downstream process and formulation development

Depending on your target product concept, we prototype a formulation to maximize product stability and performance. We confirm upstream and downstream process compatibility at scale.

Learn more about our facility and team

Fermentation Capabilities
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Downstream Process Equipment
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Analytical Instrumentation
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Scale-up Expertise
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Fermentation Capabilities

Bridge the gap from lab to commercial scale. Generate material for field trials and formulation development

Small-Scale Equipment

  • Biostore – Microbial Storage System
  • Biolector Pro and basic units and Tecan Robotics
  • Sartorius AMBR250 systems
  • 15 Sartorius Biostat 20 Liter C+ Bioreactors
  • Sartorius Bioreactor 30 L Fermenter
  • Clara 20 semi-continuous centrifuge

Pilot-Scale Equipment

  • 150L Applikon Bioreactor
  • 300L DCI Bioreactor
  • 3000L DCI Bioreactor

Get Started

Contact us, and we’ll schedule a call to answer your questions.

Downstream Process Equipment

Test processes to separate and concentrate your product in preparation for formulation

Sterile Mix and Hold

  • 3 250L DCI Sterile Addition Hold Tank w/ Agitator
  • 300L DCI Media Mix Tank w/ Agitator
  • 1,000L DCI Sterile Addition Hold Tank w/ Agitator
  • 3,000L DCI Media Mix Tank w/ Agitator

Separation & Concentration

  • Small and Large Skids for Tangential Flow Filtration: Snyder 310, Membralox Pilot
  • Westfalia Centrifuge - GEA Model TSE-10

Homogenization and Formulation Equipment

  • Spray Dryers - GEA Niro and custom build 70PK001
  • 300L Triple P Formulation Tank w/ Agitator
  • 1,000L Triple P Formulation Tank w/ Agitator
  • 3,000L Triple P Formulation Tank w/ Agitator

Get Started
Contact us, and we’ll schedule a call to answer your questions.

Analytical Instrumentation

Quantify biological chemistry. Ensure a robust, quality-controlled process and formulation for your product.

Instrumentation

  • UPLC, Triple Quad, and Echo Mass Spectrometers
  • Agilent 1260, 1200, 1100 HPLC
  • Gas Chromatography (GC)
  • LC/MS-D
  • Malvern Particle Size Analyzer
  • Raman Spectrometer

Separation & Concentration

  • Small and Large Skids for Tangential Flow Filtration: Snyder 310, Membralox Pilot
  • Westfalia Centrifuge - GEA Model TSE-10

Get Started

‍Contact us, and we’ll schedule a call to answer your questions.

Scale-up Expertise

Leverage our team to develop a commercial-ready process.

Media and Fermentation Process

  • We bring deep expertise in media and process optimization for spore-forming bacteria utilized in agricultural biologicals
  • We apply tried and tested methods for improving CFU, spore count, and active ingredient titer using through media optimization and fermentation process DoE

Downstream Process and Formulation

  • We rigorously test combinations of preservatives, stabilizers, antifoams and antifreeze inputs to separate and concentrate active ingredients more effectively
  • Our formulation development experience spans a range of ag biological product concepts including seed treatment, liquid spray, wettable granules, dry powder

Get Started

‍Contact us, and we’ll schedule a call to answer your questions.

Our team is excited to learn how Ginkgo can accelerate your product development goals. Start the conversation today.

Contact Our Team Today

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