Transgenic Traits & Optimization
The next novel plant trait is waiting to be discovered and optimized
Novelty and efficacy: a potent combination for insect control and herbicide tolerance
01
Massive metagenomic library
Discover unencumbered leads in our proprietary metagenomic library, consisting of >3.5B unique genes, most of which are not found in publicly available databases.
02
Industry-leading protein engineering expertise
Design new leads or optimize your leads using our machine learning-based protein engineering approaches. Our models are reinforced with experimental data collected over 15 years. Test leads using our high-throughput in vitro screens.
03
Tools to optimize expression of multi-gene traits
Tap our expertise in codon and promoter optimization for tightly regulated, inducible gene expression in complex eukaryotic systems.
Discover Novel Traits
Mine our metagenomic database for unencumbered leads
Your Starting Point:
A protein or enzyme “hook” to start the search
What We Offer: Early Discovery
- We use a machine learning-based model and patented enrichment and amplification techniques to comb through our metagenomic database
- The hits from this search are produced, purified, and screened in activity assays, such as insect diet bioassays
- Top performing hits undergo further evaluation
Why Ginkgo:
The likelihood of discovering a trait with novel mechanism of action and freedom to operate increases with the size of the library being mined
Get Started
Contact us, and we’ll schedule a call to answer your questions.
Optimize Leads
Improve the efficacy of your lead candidates
Your Starting Point:
Your lead candidate traits or traits identified from our metagenomic library
What We Offer: ML-based Lead Optimization
- Ginkgo’s team of protein engineering experts determine which computational tools and screening approaches are best suited to your goals
- From there, we use an iterative approach until we achieve or exceed your target performance metric:
- Our models to generate enzyme or protein variants for high-throughput in vitro screening
- Screening results are fed back into our models to inform the next iteration of designs
- You evaluate the optimized leads further
Why Ginkgo:
Our team applies high and ultra-high-throughput methods to screen leads, providing new data to inform our optimization models
Get Started
Contact us, and we’ll schedule a call to answer your questions.
Our team is excited to learn how Ginkgo can accelerate your product development goals. Start the conversation today.